ProSci

Bcl-xL Antibody [7B2.5]

Product Code:
 
PSI-99-616
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG3
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
[7B2.5]
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Flow Cytometry
Shipping:
 
blue ice
Storage:
 
Store vial at 2-8˚C
1 / 1
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PSI-99-616-0.1mg0.1mg£686.00
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Further Information

Additional Names:
Apoptosis regulator Bcl-X, Bcl-2-like 1 protein, BCL2L1
Application Note:
Bcl-xL Antibody [7B2.5] for use in flow cytometry, immunohistochemistry / immunocytochemistry, ELISA, western blotting, and immunoprecipitation assays.
Background:
Bcl-xL is a 29 kDa member of the Bcl-2 family of proteins involved in regulation of programmed cell death, or apoptosis. It is found in both soluble and membrane fractions of cellular lysates. Like Bcl-2, Bcl-xL has been demonstrated to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. While formation of heterodimers with the apoptosis-enhancing protein, Bax does not block the apoptosis-suppressing property of Bcl-xL, heterodimerization with Bad effectively inhibits the protective function of Bcl-xL.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant human Bcl-xS
NCBI Gene ID #:
598
NCBI Official Name:
BCL2-like 1
NCBI Official Symbol:
BCL2L1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
Q07817
Research Area:
Transcription,Cancer
SPECIFICITY:
Bcl-xL
Swissprot #:
Q07817
User NOte:
Optimal dilutions for each application to be determined by the researcher.