ProSci

EDG1 Antibody

Product Code:
 
PSI-33-006
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
blue ice
Storage:
 
Aliquot and Store at -20C. Avoid freez-thaw cycles.
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Western blot testing of human samples with EDG1 antibody at 4ug/ml.
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Western blot testing of human samples with EDG1 antibody at 4ug/ml.

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CodeSizePrice
PSI-33-006-100ug100ug£662.00
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This product comes from: United States.
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Further Information

Additional Names:
S1P1 Antibody: EDG1, S1P1, CD363, ECGF1, EDG-1, CHEDG1, D1S3362, EDG1, Sphingosine 1-phosphate receptor 1, Endothelial differentiation G-protein coupled receptor 1, S1P receptor 1
Application Note:
Western blot: 4-6 ug/ml

Provided assay concentrations are suggestions only, EDG1 antibody titration may be required for optimal results.
Background:
EDG1 (Endothelial differentiation gene 1), also called Sphingosine-1-phosphate receptor 1 (S1PR1) is the G-protein coupled receptor for Sphingosine 1-phosphate (S1P). Via its interaction with S1P, EDG1 is involved in a number of cellular processes. The binding of S1P leads to angiogenesis and tumor cell motility in cancer, and this interaction also participates in the formation of cell-cell adherens junctions. During embryogenesis, it regulates vascularization. EDG1 interacts with the serotonin receptor 5-HT1AR in the central nervous system. It is also a regulator of innate and adaptive immunity by signaling the release of T-cells from lymph nodes.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A recombinant protein fragment from the C-terminal portion of human EDG1 was used as the immunogen for this antibody.
NCBI Gene ID #:
1901
NCBI Official Name:
sphingosine-1-phosphate receptor 1
NCBI Official Symbol:
S1PR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein A affinity chromatography
Research Area:
Immunology
Swissprot #:
P21453
User NOte:
Optimal dilutions for each application to be determined by the researcher