Ancell

CD244(2B4) (human)-muIg Fusion Protein (preservative free)

Product Code:
 
ANC-544-820
Product Group:
 
Recombinant Proteins
Supplier:
 
Ancell
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
BI
Storage:
 
+4°C
 

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ANC-544-820-25ug25 ug£473.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
2B4; SLAMF4
Concentration:
0.5mg/ml
EClass:
32160000
Form (Short):
liquid
Formulation:
50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl
Handling Advice:
Avoid freeze/thaw cycles.
Labels - Conjugates:
Preservative Free
Long Description:
Recombinant protein. Source/Host: CHO cells. Purity: . 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl CD244 (2B4, SLAMF4) is a 66 kD member of the CD2/SLAM related receptor family (SRR). It is expressed on NK, T cell subsets, monocytes and eosinophils. It is expressed at high levels on Leuikemia initiating cells, and plays a role in their proliferative potential. In mice there are two transcription varients, a long form and a short form of CD244 each of which have distinct signaling properties. In humans, only the long form is expressed. Decreased CD244 expression on monocytes of SLE patients correlated (negatively) with autoantibody titers. CD244 mediated function in immune response can vary greatly dependant on the context of its ligation.
Molecular Weight:
~135kDa (native dimer)
Package Type:
Plastic Vial
Product Description:
CD244 (2B4, SLAMF4) is a 66 kD member of the CD2/SLAM related receptor family (SRR). It is expressed on NK, T cell subsets, monocytes and eosinophils. It is expressed at high levels on Leuikemia initiating cells, and plays a role in their proliferative potential. In mice there are two transcription varients, a long form and a short form of CD244 each of which have distinct signaling properties. In humans, only the long form is expressed. Decreased CD244 expression on monocytes of SLE patients correlated (negatively) with autoantibody titers. CD244 mediated function in immune response can vary greatly dependant on the context of its ligation.
Source / Host:
CHO cells
Specificity:
Binds to recombinant CD48 in EIA and cell surface CD48 on Raji cell surface in FACS.
TAGs:
Fc
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at +4°C.