Ropivacaine hydrochloride monohydrate
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This product comes from:
Switzerland.
Typical lead time:
7-10 working days.
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Further Information
Alternate Names/Synonyms:
LEA 103; Naropin; (S)-Ropivacaine hydrochloride monohydrate
White to off-white powder.
132112-35-7
32160000
liquid
GHS05
H318
InChI=1S/C17H26N2O.ClH.H2O/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;;/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20);1H;1H2
VSHFRHVKMYGBJL-UHFFFAOYSA-N
Chemical. CAS: 132112-35-7. Formula: C17H26N2O . HCl . H2O. MW: 274.4 . 36.5 . 18.0. Synthetic. Ropivacaine is a long-acting amide local anaesthetic agent. Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers. It is a pure S(-)enantiomer and less lipophilic than racemic sodium channel blockers, such as bupivacaine and is less likely to penetrate large myelinated motor fibres, resulting in a relatively reduced motor blockade. Thus, ropivacaine has a greater degree of motor sensory differentiation, which could be useful when motor blockade is undesirable. The reduced lipophilicity is also associated with decreased potential for central nervous system toxicity and cardiotoxicity.
MFCD00946578
C17H26N2O . HCl . H2O
274.4 . 36.5 . 18.0
Vial
P280, P305+P351+P338, P310
Ropivacaine is a long-acting amide local anaesthetic agent. Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers. It is a pure S(-)enantiomer and less lipophilic than racemic sodium channel blockers, such as bupivacaine and is less likely to penetrate large myelinated motor fibres, resulting in a relatively reduced motor blockade. Thus, ropivacaine has a greater degree of motor sensory differentiation, which could be useful when motor blockade is undesirable. The reduced lipophilicity is also associated with decreased potential for central nervous system toxicity and cardiotoxicity.
>98% (T)
Danger
CC1=CC=CC(C)=C1NC(C2CCCCN2CCC)=O.O.Cl
Soluble in DMSO (25mg/mL), DMF (15mg/ml), ethanol (15mg/ml), methanol or water (2mg/ml).
Synthetic
Non-hazardous
Biochemical Reagents
12352200
Stable for at least 2 years after receipt when stored at +4°C.