Amikacin hydrate
Product Code:
CDX-A0287
CDX-A0287
Regulatory Status:
RUO
RUO
Shipping:
Ambient
Ambient
Storage:
+4°C
+4°C
No additional charges, what you see is what you pay! *
| Code | Size | Price |
|---|
| CDX-A0287-G005 | 5 g | £121.00 |
Quantity:
Prices exclude any Taxes / VAT
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: Switzerland.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
- Further Information
- Documents
- References
- Show All
Further Information
Alternate Names/Synonyms:
N1-[(S)-4-Amino-2-hydroxybutyryl]kanamycin A; Amicacin; Amikacillin; Amukin; Antibiotic BB-K 8; BAY 41-6551; BAY 416651
Appearance:
White crystalline powder.
CAS:
1257517-67-137517-28-5 (anhydrous)
EClass:
32160000
Form (Short):
solid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C22H43N5O13/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+/m0/s1
InChiKey:
LKCWBDHBTVXHDL-RMDFUYIESA-N
Long Description:
Chemical. CAS: 1257517-67-1 | 37517-28-5 (anhydrous). Formula: C22H43N5O13 . xH2O. MW: 585.60 (anhydrous basis). Broad-spectrum semisynthetic aminoglycoside antibiotic derived from kanamycin A, which is effective against Gram-negative and Gram-positive bacteria. Aminoglycoside antibiotics bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation, consequently inhibiting bacterial protein synthesis. Commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (ASTs, panels, discs, and MIC strips) of organisms such as Mycobacterium tuberculosis and Ehrlichia phagocytophila.
MDL:
MFCD11045969
Molecular Formula:
C22H43N5O13 . xH2O
Molecular Weight:
585.60 (anhydrous basis)
Package Type:
Vial
Product Description:
Broad-spectrum semisynthetic aminoglycoside antibiotic derived from kanamycin A, which is effective against Gram-negative and Gram-positive bacteria. Aminoglycoside antibiotics bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation, consequently inhibiting bacterial protein synthesis. Commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (ASTs, panels, discs, and MIC strips) of organisms such as Mycobacterium tuberculosis and Ehrlichia phagocytophila.
Purity:
>97% (NMR)
SMILES:
O[C@@H]1[C@@H](CN)O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@@H]3[C@H](O)[C@@H](N)[C@H](O)[C@@H](CO)O3)[C@H](NC([C@H](CCN)O)=O)C[C@@H]2N)[C@H](O)[C@H]1O
Solubility Chemicals:
Soluble in water (10mg/ml).
Source / Host:
Semisynthetic
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
Documents
References
(1) H. Kawaguchi, et al.; J. Antibiot. 25, 695 (1972) | (2) K.E. Price, et al.; Antimicrob. Agents Chemother. 5, 143 (1974) | (3) N.S. Brewer; Mayo Clin. Proc. 52, 675 (1977) | (4) R.N. Jones, et al.; Antimicrob. Agents Chemother. 22, 985 (1982) | (5) A.M. Ristuccia & B.A. Cunha; Ther. Drug Monit. 7, 12 (1985) | (6) B.D. Davis; Microbiol. Rev. 51, 341 (1987) | (7) B.A. Cunha; Med. Clin. North Am. 90, 1089 (2006) | (8) M.S. Ramirez & M.E. Tolmasky; Molecules 22, E2267 (2017)