Cathepsin Antibody / L-V-K-H

Western blot: 1:500-1:2000

Optimal dilution of the Cathepsin L/V/K/H antibody should be determined by the researcher.

Cathepsins are proteases (enzymes that degrade proteins) found in all animals as well as other organisms. There are approximately a dozen members of this family, which are distinguished by their structure, catalytic mechanism, and which proteins they cleave. Most of the members become activated at the low pH found in lysosomes. Thus, the activity of this family lies almost entirely within those organelles. There are, however, exceptions such as cathepsin K, which works extracellularly after secretion by osteoclasts in bone resorption. Cathepsins have a vital role in mammalian cellular turnover. [Wiki]

Purified

Antibody in PBS with 0.02% sodium azide and 50% glycerol

A synthetic peptide common to human Cathepsin L/V/K/H was used as the immunogen for the Cathepsin L/V/K/H antibody.

This Cathepsin L/V/K/H antibody is available for research use only.

Affinity purified

Human, Mouse, Rat

P07711