CD123 [IL-3Ralpha] (human)-muIg Fusion Protein (preservative free)
Product Code:
ANC-545-820
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This product comes from:
Switzerland.
Typical lead time:
10-14 working days.
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Further Information
Alternate Names/Synonyms:
Interleukin-3 Receptor alpha
0.5mg/ml
32160000
liquid
50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl
Avoid freeze/thaw cycles.
Preservative Free
Protein. A soluble molecule consisting of the extracellular domain of mature human CD123 fused to murine IgG2a Fc. Source: CHO cells. Liquid. 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl. Human CD123 (Interleukin-3 Receptor alpha) is a 70kDa type I transmembrane molecule, and is the low affinity receptor for the cytokine IL-3, which can stimulate proliferation or differentiation. When paired in a heterodimer with CD131 (IL-3Rbeta), it binds IL-3 with much higher affinity. CD123 is found on myeloid precusors, stem cells, a subset of T cells, some B cells, megakaryocytes, basophils, monocytes and epithelial cells. CD123 is present at high levels on many hematologic malignancies, and antibodies and CAR T cells against CD123 have been used successfully to combat acute myeloid leukemia (AML).
Plastic Vial
Human CD123 (Interleukin-3 Receptor alpha) is a 70kDa type I transmembrane molecule, and is the low affinity receptor for the cytokine IL-3, which can stimulate proliferation or differentiation. When paired in a heterodimer with CD131 (IL-3Rbeta), it binds IL-3 with much higher affinity. CD123 is found on myeloid precusors, stem cells, a subset of T cells, some B cells, megakaryocytes, basophils, monocytes and epithelial cells. CD123 is present at high levels on many hematologic malignancies, and antibodies and CAR T cells against CD123 have been used successfully to combat acute myeloid leukemia (AML).
A soluble molecule consisting of the extracellular domain of mature human CD123 fused to murine IgG2a Fc.
CHO cells
Fc
Non-hazardous
Other Proteins
12352202
Stable for at least 6 months after receipt when stored at +4°C.
