ProSci

ALAS1 Antibody

Product Code:
 
PSI-15-004
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Shipping:
 
Blue Ice or RT
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunofluorescence analysis of HeLa cells using ALAS1 antibody (15-004). Blue: DAPI for nuclear staining.
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Immunofluorescence analysis of HeLa cells using ALAS1 antibody (15-004). Blue: DAPI for nuclear staining.

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PSI-15-004-50uL50uL£433.00
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Further Information

Additional Names:
ALAS1, ALAS, ALAS3, ALASH, MIG4
Application Note:
WB: 1:500 - 1:2000

IF: 1:50 - 1:200
Background:
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ALAS1 (NP_954635.1).
NCBI Gene ID #:
211
NCBI Official Name:
aminolevulinate, delta-, synthase 1
NCBI Official Symbol:
ALAS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Cancer, Signal Transduction
Swissprot #:
P13196
User NOte:
Optimal dilutions for each application to be determined by the researcher.