Antibody Clonality:
Polyclonal
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
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This product comes from:
United States.
Typical lead time:
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Further Information
PTCH1, PTC, BCNS, HPE7, PTC1, PTCH, NBCCS, PTCH11
WB: 1:500 - 1:2000
IF: 1:50 - 1:200
This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 770-970 of human PTCH1 (NP_000255.2).
5727
patched 1
PTCH1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 180kDa
Affinity purification
Cancer, Cell Cycle, Neuroscience, Signal Transduction, Stem Cell
Q13635
Optimal dilutions for each application to be determined by the researcher.