Further Information
EDF, TRF, IL-5Interleukin-5, B-cell differentiation factor I, IL-5
WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 20-134 of human IL5 (NP_000870.1).
3567
interleukin 5 (colony-stimulating factor, eosinophil)
IL5
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 13kDa
Affinity purification
Cancer, Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Innate Immunity
P05113
Optimal dilutions for each application to be determined by the researcher.
