ProSci

M-CSF Recombinant Protein (Animal Free)

Product Code:
 
PSI-40-769
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Shipping:
 
Blue Ice or room temp
Storage:
 
The recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
 

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PSI-40-769-2ug2ug£324.00
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
Macrophage Colony Stimulating Factor, CSF-1, MGI-IM
Background:
M-CSF is a potent hematopoietic factor produced by a variety of cells, including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is a key regulator of cellular proliferation, differentiation, and survival for blood monocytes, tissue macrophages, and their respective progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness and fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation. Human M-CSF is reactive in murine systems, but the murine molecule exhibits no activity on human cells. Recombinant Rat M-CSF is a 36.2 kDa homodimeric protein consisting of two 155 amino acid polypeptide subunits.
Biological Activity:
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells is < 5.0 ng/ml, corresponding to a specific activity of > 2 x 105 units/mg.
NCBI Gene ID #:
78965
NCBI Official Name:
colony stimulating factor 1 (macrophage)
NCBI Official Symbol:
Csf1
NCBI Organism:
Rattus norvegicus
Physical State:
Lyophilized
Purity:
> 98% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q8JZQ0

Documents