ProSci

SARS-CoV-2 (COVID-19) NSP8 Recombinant Protein

Product Code:
 
PSI-97-097
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Virus
Application:
 
Western Blot (WB)
Storage:
 
Working aliquots should be stored at -70˚C or lower. Avoid repeated freeze-thaw cycles.
 

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PSI-97-097-0.1mg0.1mg£854.00
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Further Information

Additional Names:
NSP8,?nsp8,?Non-structural protein 8,?COVID-19
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
NSP8, forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 coronavirus. By investigating the entire proteome of SARS-CoV-2, six proteins, including the S protein and five non-structural proteins (nsp3, 3CL-pro, and nsp8-10) were predicted to be adhesins, which are crucial to the viral adhering and host invasion. The S, nsp3, and nsp8 proteins were also predicted by Vaxign-ML to induce high protective antigenicity.
Background References:
  • te Velthuis AJ, et al. Nucleic Acids Res. 2012. 40(4):1737-47.
  • Edison Ong, et al. doi.org. 2020. 000141.
Buffer:
20 mM Tris, 250 mM NaCl, pH8.5 with glycerol?
Fusion Tag:
His Tag at N-terminus
Physical State:
Liquid
Predicted Molecular Weight:
22-25 kDa
Protein Accession #:
YP_009725304.1
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli

Documents