ProSci

Netrin receptor DCC / DCC Recombinant Protein

Product Code:
 
PSI-11-185
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Human
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
blue ice or RT
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-11-185-0.1mg0.1mg£729.00
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Further Information

Additional Names:
Netrin receptor DCC,DCC,IGDCC1,netrin receptor DCC
Application Note:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 119.6 kDa. The protein migrates as 125-150 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.
Background References:
  • K Keino-Masu, et al. Cell. 1996. 87(2):175-85.
  • S Miyake, et al. Cancer Res. 1994. 54(11):3007-10.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
1630
NCBI Official Name:
DCC netrin 1 receptor
NCBI Official Symbol:
DCC
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
119.6 kDa
Protein Accession #:
NP_005206.2
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
P43146

Documents