ProSci

B7-H3 (4Ig) / B7-H3b Recombinant Protein

Product Code:
 
PSI-11-422
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Human
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
 
blue ice or RT
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-11-422-0.1mg0.1mg£657.00
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This product comes from: United States.
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Further Information

Additional Names:
4Ig-B7-H3,B7-H3,CD276,PSEC0249,UNQ309/PRO352,B7 homolog 3
Application Note:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 48.5 kDa. The protein migrates as 65-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
Human B7 homolog 3 (B7-H3) is a member of the B7 family of immune proteins that provide signals for the regulation of immune responses. Other family members include B7-1, B7-2, B7-H1/PD-L1, B7-H2, and PD-L2. B7 family proteins are type I transmembrane immunoglobulin (Ig) superfamily members that contain extracellular Ig V-like and Ig C-like domains with a short cytoplasmic tail. Termed 4IgB7-H3 or B7-H3b, this molecule has two additional Ig-like domains (one V-type and one C-type) and shows a ubiquituous expression pattern.
Background References:
  • Chapoval AI., et al. 2001, Nat Immunol., 2(3), 269-74.
  • Steinberger P., et al. 2004, J Immunol., 172(4), 2352-9.
  • Sun M., et al. 2002, J Immunol., 168(12), 6294-7.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
80381
NCBI Official Name:
CD276 molecule
NCBI Official Symbol:
CD276
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
48.5 kDa
Protein Accession #:
NP_001019907.1
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
Q5ZPR3

Documents