L-Proline
Product Code:
CDX-P0446
CDX-P0446
Regulatory Status:
RUO
RUO
Shipping:
AMBIENT
AMBIENT
Storage:
+20°C
+20°C
No additional charges, what you see is what you pay! *
Code | Size | Price |
---|
CDX-P0446-G100 | 100 g | £102.00 |
Quantity:
CDX-P0446-K001 | 1 kg | £560.00 |
Quantity:
Prices exclude any Taxes / VAT
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: Switzerland.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
- Further Information
- Documents
- References
- Show All
Further Information
Alternate Names/Synonyms:
(S)-Pyrrolidine-2-carboxylic acid; H-Pro-OH
Appearance:
White to off-white powder.
CAS:
147-85-3
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1
InChiKey:
ONIBWKKTOPOVIA-BYPYZUCNSA-N
Long Description:
Chemical. CAS: 147-85-3. Formula: C5H9NO2. MW: 115.13. Synthetic. Proline is a proteinogenic amino acid that is used in the biosynthesis of proteins. L-Proline has been found to act as a weak agonist of the glycine receptor and of both NMDA and non-NMDA (AMPA/kainate) ionotropic glutamate receptors. L-proline is essential for induction of hepatocyte proliferation in culture, through its affect on synthesis of intracellular collagen. It has free radical scavenging potential. Induces differentiation of embyonic stem cells and has been studied as regulator of pluripotent cells in culture. Shows cryoprotective properties. L-Proline is used as asymmetric catalysts in organic synthesis and asymmetric aldol cyclization. It is involved in the Michael addition of dimethyl malonate to alfa-beta-unsaturated aldehydes. It finds uses in pharmaceutical, biotechnological applications due to its osmoprotectant property.
MDL:
MFCD00064318
Molecular Formula:
C5H9NO2
Molecular Weight:
115.13
Package Type:
Vial
Product Description:
Proline is a proteinogenic amino acid that is used in the biosynthesis of proteins. L-Proline has been found to act as a weak agonist of the glycine receptor and of both NMDA and non-NMDA (AMPA/kainate) ionotropic glutamate receptors. L-proline is essential for induction of hepatocyte proliferation in culture, through its affect on synthesis of intracellular collagen. It has free radical scavenging potential. Induces differentiation of embyonic stem cells and has been studied as regulator of pluripotent cells in culture. Shows cryoprotective properties. L-Proline is used as asymmetric catalysts in organic synthesis and asymmetric aldol cyclization. It is involved in the Michael addition of dimethyl malonate to alfa-beta-unsaturated aldehydes. It finds uses in pharmaceutical, biotechnological applications due to its osmoprotectant property.
Purity:
>98% (HPLC)
SMILES:
O=C(O)[C@H]1NCCC1
Solubility Chemicals:
Soluble in water (50 mg/ml) or ethanol.
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at RT.
Documents
References
(1) A. Van Harreveld & F. Strumwasser F.; Neuroscience 6, 2495 (1981) | (2) E. Keller, et al.; J. Neurochem. 37, 1335 (1981) | (3) T. Nakamura, et al.; BBRC 122, 884 (1984) | (4) V. Henzi, et al.; Mol. Pharmacol. 41, 793 (1992) | (5) S. Usse, et al.; J. Org. Chem. 65, 914 (2000) | (6) S. Kaul, et al.; Amino Acids 34, 315 (2008) | (7) N. Verbruggen & C. Hermans; Amino Acids 35, 753 (2008) (Review) | (8) J.M. Washington, et al.; Am. J. Physiol. Cell Physiol. 298, C982 (2010) | (9) G. Zhang, et al.; Chem. Commun. 49, 7908 (2013) | (10) S. Comes, et l.; Stem Cell Reports 1, 307 (2013) | (11) H. Jin, et al.; J. Org. CHem. 81, 3263 (2016) | (12) L. Zahng, et al.; Sci. Rep. 6, 26326 (2016)