Dexmedetomidine hydrochloride
Product Code:
CDX-D0792
CDX-D0792
Regulatory Status:
RUO
RUO
Shipping:
AMBIENT
AMBIENT
Storage:
+4°C
+4°C
No additional charges, what you see is what you pay! *
| Code | Size | Price |
|---|
| CDX-D0792-M010 | 10 mg | £65.00 |
Quantity:
| CDX-D0792-M050 | 50 mg | £230.00 |
Quantity:
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* Rare exceptions are clearly labelled (only 0.14% of items!).
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This product comes from: Switzerland.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
- Further Information
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Further Information
Alternate Names/Synonyms:
Dex; Precedex; (+)-Medetomidine hydrochloride; (S)-Medetomidine hydrochloride; 4-[(S)-alpha,2,3-Trimethylbenzyl]imidazole monohydrochloride
Appearance:
White to beige powder.
CAS:
145108-58-3
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H302-H315-H319-H335
InChi:
InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H/t11-;/m0./s1
InChiKey:
VPNGEIHDPSLNMU-MERQFXBCSA-N
Long Description:
Chemical. CAS: 145108-58-3. Formula: C13H16N2 ? HCl. MW: 236.74. Dexmedetomidine hydrochloride is the active isomer of medetomidine and is a highly potent and selective alpha2-adrenergic agonist (Ki values are 1.08 and 1750 nM for alpha2- and alpha1-adrenoceptors respectively) with analgesic and sedative properties. Dexmedetomidine hydrochloride is used clinically as an anesthetic agent to reduce anxiety and tension and promote relaxation and sedation without causing respiratory depression. It is active in vivo; displays hypotensive, bradycardic, sedative, anxiolytic, hypothermic and analgesic effects.
MDL:
MFCD12912677
Molecular Formula:
C13H16N2 ? HCl
Molecular Weight:
236.74
Package Type:
Vial
Precautions:
P261-P305 + P351 + P338
Product Description:
Dexmedetomidine hydrochloride is the active isomer of medetomidine and is a highly potent and selective alpha2-adrenergic agonist (Ki values are 1.08 and 1750 nM for alpha2- and alpha1-adrenoceptors respectively) with analgesic and sedative properties. Dexmedetomidine hydrochloride is used clinically as an anesthetic agent to reduce anxiety and tension and promote relaxation and sedation without causing respiratory depression. It is active in vivo; displays hypotensive, bradycardic, sedative, anxiolytic, hypothermic and analgesic effects.
Purity:
>98% (HPLC)
Signal word:
Warning
SMILES:
CC1=C(C)C([C@@H](C2=CN=C[NH2+]2)C)=CC=C1.[Cl-]
Solubility Chemicals:
Soluble in water (10mg/ml), ethanol (25mg/ml) or DMSO (20mg/ml).
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
Documents
References
(1) R. Virtanen, et al.; Eur. J. Pharmacol. 150, 9 (1988) | (2) H. Scheinin, et al.; Prog. Neuropsychopharm. Biol. Psychiat. 13, 635 (1989) (Review) | (3) R. Gertler, et al.; Proc. (Bayl. Univ. Med. Cent.) 14, 13 (2001) | (4) S. Bajwa & A. Kulshrestha; Ann. Med. Health Sci. Res. 3, 475 (2013) | (5) Y. Cai, et al.; Mol. Med. Rep. 9, 1542 (2014) (Review) | (6) M. Maze; Anesthesiology 125, 590 (2016) (Review) | (7) C. Tang & Z. Xia; J. Pain Res. 10, 1899 (2017) (Review)