Storage:
Short Term: +20°C, Long Term: +4°C
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This product comes from:
Switzerland.
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Further Information
Alternate Names/Synonyms:
3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide; CCRG 81045; MB 39831; Methazolastone; NSC 362856; Temodal
White to light pink powder.
85622-93-1
32160000
liquid
GHS07,GHS08
Protect from light and moisture.
H302-H315-H319-H335-H350-H360
InChI=1S/C6H6N6O2/c1-11-6(14)12-2-8-3(4(7)13)5(12)9-10-11/h2H,1H3,(H2,7,13)
BPEGJWRSRHCHSN-UHFFFAOYSA-N
Chemical. CAS: 85622-93-1. Formula: C6H6N6O2. MW: 194.15. Temozolomide is a DNA methylating agent and drug resistance-modifying agent with antitumor and antiangiogenic properties. Temozolomide induces G2/M arrest and apoptosis through adduction of a methyl group to O6 position of guanine in genomic DNA and interfering with DNA replication and leading to cytotoxicity in proliferating cells. It has been shown to induce autophagy in malignant glioma cells. It is effective in a variety of types of cancer, including aggressive brain cancers.
MFCD00866492
C6H6N6O2
194.15
Vial
P201-P261-P305 + P351 + P338-P308 + P313
Temozolomide is a DNA methylating agent and drug resistance-modifying agent with antitumor and antiangiogenic properties. Temozolomide induces G2/M arrest and apoptosis through adduction of a methyl group to O6 position of guanine in genomic DNA and interfering with DNA replication and leading to cytotoxicity in proliferating cells. It has been shown to induce autophagy in malignant glioma cells. It is effective in a variety of types of cancer, including aggressive brain cancers.
>98% (HPLC)
Danger
O=C1N(C)N=NC2=C(C(N)=O)N=CN21
Soluble in DMSO (5mg/ml) or DMF (5mg/ml).
Non-hazardous
Biochemical Reagents
12352200
Stable for at least 2 years after receipt when stored at +4°C.