Storage:
Short Term: +4°C, Long Term: -20°C
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Further Information
Alternate Names/Synonyms:
17-Phenyl-tri-norprostaglandin F2alpha-ethyl amide; cGMP Bimatoprost; AGN-192024; Lumigan; Prostamide
White powder.
155206-00-1
32160000
liquid
Protect from light and moisture.
InChI=1S/C25H37NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,20-24,27-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t20-,21+,22+,23-,24+/m0/s1
AQOKCDNYWBIDND-FTOWTWDKSA-N
Chemical. CAS: 155206-00-1. Formula: C25H37NO4. MW: 415.57. Bimatoprost is a synthetic prostamide FP receptor agonist, structurally related to prostaglandin F2alpha that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma. Bimatoprost is therefore an antiglaucoma agent. Bimatoprost is converted by an amidase enzymatic activity to yield the corresponding free acid, 17-phenyl trinor PGF2alpha, a potent PGF2alphaR agonist. In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity.
MFCD03411999
C25H37NO4
415.57
Vial
Bimatoprost is a synthetic prostamide FP receptor agonist, structurally related to prostaglandin F2alpha that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma. Bimatoprost is therefore an antiglaucoma agent. Bimatoprost is converted by an amidase enzymatic activity to yield the corresponding free acid, 17-phenyl trinor PGF2alpha, a potent PGF2alphaR agonist. In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity.
>95% (HPLC)
O[C@H]1C[C@@H](O)[C@H](/C=C/[C@@H](O)CCC2=CC=CC=C2)[C@H]1C/C=CCCCC(NCC)=O
Soluble in DMSO.
Non-hazardous
Biochemical Reagents
12352200
Stable for at least 2 years after receipt when stored at -20°C.