NSJ Bioreagents

Beta-2 Microglobulin Antibody

Product Code:
 
NSJ-V2802
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2b, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
BBM.1
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Western Blot (WB)
Storage:
 
Store the Beta-2 Microglobulin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
1 / 2
Immunofluorescent staining of human HeLa cells with Beta-2 Microglobulin antibody (green, clone BBM.1) and Reddot nuclear stain (red).~
2 / 2
Western blot testing of human Raji cell lysate with Beta-2 Microglobulin antibody (clone BBM.1). Expe
❮❯

Immunofluorescent staining of human HeLa cells with Beta-2 Microglobulin antibody (green, clone BBM.1) and Reddot nuclear stain (red).~
Western blot testing of human Raji cell lysate with Beta-2 Microglobulin antibody (clone BBM.1). Expe

No additional charges, what you see is what you pay! *

CodeSizePrice
NSJ-V2802-20UG20 ug£264.00
Quantity:
NSJ-V2802-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Application Details :
Flow cytometry: 1-2ug/million cells,Western blot: 1-2ug/ml,Immunohistochemistry (Frozen): 1-2ug/ml for 30 min at RT
Application Note:
Optimal dilution of the Beta-2 Microglobulin antibody should be determined by the researcher.
Description:
Recognizes a protein of 12kDa, identified as microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha- heavy chain that contains three subdomains (alpha-1, alpha-2, alpha-3) and a non-covalent associating light chain, known as beta-2-Microglobulin. Beta-2-Microglobulin associates with the alpha-3 subdomain of the alpha- heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha-1 and alpha-2 domains of the alpha- heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Immunogen:
MOLT-4 human T cell line was used as the immunogen for the Beta-2 Microglobulin antibody.
Limitation:
This Beta-2 Microglobulin antibody is available for research use only.
Localization:
Cytoplasmic
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
P61769