NSJ Bioreagents

Langerin Antibody / CD207

Product Code:
 
NSJ-V7993
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2a, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
LGRN/1821
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Store the Langerin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using Langerin antibody (clone LGRN/1821). These results demonstrate the foremost specificity of the LGRN/1821 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a
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Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using Langerin antibody (clone LGRN/1821). These results demonstrate the foremost specificity of the LGRN/1821 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a

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NSJ-V7993-20UG20 ug£264.00
Quantity:
NSJ-V7993-100UG100 ug£534.00
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Further Information

Application Details :
ELISA (order BSA-free format for coating),Western blot: 1-2ug/ml
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.
Format :
Purified
Formulation :
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A recombinant human partial protein (amino acids 74-213) was used as the immunogen for the Langerin antibody.
Limitation:
This Langerin antibody is available for research use only.
Localization:
Cell surface, cytoplasmic
Microarray Validated?:
Yes
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
Q9UJ71