NSJ Bioreagents

Phospho-FAS Antibody (pY291)

Product Code:
 
NSJ-F48476
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Dot Blot
  • Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
 
Aliquot the phospho-FAS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Dot blot analysis of phospho-FAS antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted. P-Pab=phos-Ab; P-Peptide=phos-peptide; NP-Peptide=nonphos-peptide.

Dot blot analysis of phospho-FAS antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted. P-Pab=phos-Ab; P-Peptide=phos-peptide; NP-Peptide=nonphos-peptide.

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CodeSizePrice
NSJ-F48476-0.08ML0.08 ml£260.00
Quantity:
NSJ-F48476-0.4ML0.4 ml£502.00
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details :
Dot blot: 1:500
Application Note:
Titration of the phospho-FAS antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). [UniProt]
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
This phospho-FAS antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY291 of human FAS.
Limitation:
This phospho-FAS antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P25445