NSJ Bioreagents

GMPS Antibody / GMP Synthase

Product Code:
 
NSJ-RQ6255
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
  • Western Blot (WB)
Storage:
 
After reconstitution, the GMP Synthase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
1 / 2
Flow cytometry testing of human HeLa cells with GMP Synthase antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= GMP Synthase antibody.
2 / 2
Western blot testing of human 1) HEK293, 2) A431, 3) HL60, 4) COLO-320, 5) Raji, 6) ThP-1, 7) Jurkat, 8) K562, 9) rat PC-12 and 10) mouse thymus lysate with GMP Synthase antibody. Predicted molecular weight ~77 kDa.

Flow cytometry testing of human HeLa cells with GMP Synthase antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= GMP Synthase antibody.
Western blot testing of human 1) HEK293, 2) A431, 3) HL60, 4) COLO-320, 5) Raji, 6) ThP-1, 7) Jurkat, 8) K562, 9) rat PC-12 and 10) mouse thymus lysate with GMP Synthase antibody. Predicted molecular weight ~77 kDa.

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CodeSizePrice
NSJ-RQ6255-100ug100 ug£535.00
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This product comes from: United States.
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Further Information

Application Details :
Western blot: 1-2ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the GMP Synthase antibody should be determined by the researcher.
Description:
Guanosine monophosphate synthetase, also known as GMPS is an enzyme that converts xanthosine monophosphate to guanosine monophosphate. In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
A human recombinant partial protein (amino acids H21-K671) was used as the immunogen for the GMP Synthase antibody.
Limitation:
This GMP Synthase antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
P49915