ProSci

Anti IL1RL1/ST2(C2244) Antibody, Monoclonal

Product Code:
 
PSI-21-875
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Hamster
Antibody Isotype:
 
Human IgG
Antibody Clonality:
 
Recombinant Antibody
Regulatory Status:
 
RUO
Storage:
 
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at +4?C short term (1-2 weeks). Store at -20 ?C 12 months. Store at -80?C long term.
 

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PSI-21-875-0.1mg0.1mg£657.00
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Further Information

Additional Names:
C2244, T1; ST2; DER4; ST2L; ST2V; FIT-1; IL33R
Background:
Recombinant Human Antibody (C2244) is capable of binding to ST2L, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-ST2L mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-ST2L proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family. IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 possibly involved in helper T-cell function. IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.
Buffer:
PBS buffer pH 7.5
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Humanized / IL1RL1/ST2 [Homo sapiens]
NCBI Gene ID #:
9173
NCBI Official Name:
interleukin 1 receptor like 1
NCBI Official Symbol:
IL1RL1
NCBI Organism:
Homo sapiens
Protein Accession #:
Q01638
Purification:
>95%
Purity:
>95%
Research Area:
Drug Analogues
Source:
XtenCHO
Swissprot #:
Q01638
User NOte:
For research use only .