ProSci

NCOA4 (IN) Peptide

Product Code:
 
PSI-9663P
Product Group:
 
Peptides
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Blocking
Storage:
 
Store NCOA4 (IN) Peptide at -20˚C, stable for one year.
 

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CodeSizePrice
PSI-9663P-0.05mg0.05mg£166.00
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Further Information

Additional Names:
NCOA4 Antibody: Nuclear receptor coactivator 4, NCoA-4, Androgen receptor coactivator 70 kDa protein, 70 kDa AR-activator, 70 kDa androgen receptor coactivator, Androgen receptor-associated protein of 70 kDa, Ret-activating protein ELE1, ARA70, ELE1, RFG
Application Note:
NCOA4 (IN) Peptideis used for blocking the activity of theNCOA4 (IN) Antibody
Background:
NCOA4 Antibody: Study showed that NCOA4-mediated ferritin complex degradation supplies iron to mitochondria. Loss of COPZ1 induces NCOA4 mediated autophagy and ferroptosis in glioblastoma cell lines. NCOA4-mediated ferritinophagy promoted inflammatory responses in periodontitis. Low expression of ferritinophagy-related NCOA4 gene in relation to unfavorable outcome and defective immune cells infiltration in clear cell renal carcinoma.
Background References:
  • Fujimaki et al. Mol Cell Biol. 2019; 39(14): e00010-19
  • Zhang et al. Oncogene. 2021; 40(8): 1425-1439
  • Guo et al. J Periodontal Res. 2021; 56(3): 523-534
  • Mou et al. BMC Cancer. 2021; 21(1):18
Buffer:
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Concentration:
200 ug/mL
NCBI Gene ID #:
8031
NCBI Official Name:
nuclear receptor coactivator 4
NCBI Official Symbol:
NCOA4
NCBI Organism:
Homo sapiens
Peptide aa Location:
13 amino acids near the center of NCOA4 (IN).
Physical State:
Liquid
Protein Accession #:
Q13772
Protein GI Number:
8928226
Swissprot #:
Q13772
User Note:
Optimal dilutions for each application to be determined by the researcher.

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