TargetMol

AZD-8529 mesylate

Product Code:
 
TAR-T10432L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10432L-1mg1mg£138.00
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TAR-T10432L-5mg5mg£213.00
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TAR-T10432L-1mL1 mL * 10 mM (in DMSO)£257.00
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TAR-T10432L-10mg10mg£303.00
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TAR-T10432L-25mg25mg£535.00
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TAR-T10432L-50mg50mg£740.00
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TAR-T10432L-100mg100mg£994.00
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Further Information

Bioactivity:
AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM). It shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes.
CAS:
1314217-69-0
Formula:
C25H28F3N5O6S
Molecular Weight:
583.58
Pathway:
Neuroscience
Purity:
0.995
SMILES:
CS(O)(=O)=O.Cc1cc(cc2CN(Cc3ccc(OC(F)(F)F)cc3)C(=O)c12)-c1nc(CN2CCNCC2)no1
Target:
GluR

References

1. Justinova Z, et al. The Novel Metabotropic Glutamate Receptor 2 Positive Allosteric Modulator, AZD8529, Decreases Nicotine Self-Administration and Relapse in Squirrel Monkeys. Biol Psychiatry. 2015 Oct 1;78(7):452-62.