TargetMol

BPH-1358

Product Code:
 
TAR-T10586L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10586L-1mg1mg£177.00
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TAR-T10586L-5mg5mg£313.00
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TAR-T10586L-10mg10mg£434.00
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TAR-T10586L-25mg25mg£617.00
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TAR-T10586L-50mg50mg£890.00
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TAR-T10586L-100mg100mg£1,171.00
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Quantity:
TAR-T10586L-500mg500mg£2,263.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BPH-1358 (NSC50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. With IC50s of 1.8 μM and 110 nM, respectively. And it is active against S. aureus in vitro (MIC ~250 ng/mL)[1][2].
CAS:
5352-53-4
Formula:
C32H30Cl2N6O2
Molecular Weight:
601.53
Pathway:
Microbiology/Virology;
Purity:
0.98
SMILES:
Cl.Cl.O=C(Nc1cccc(c1)C1=NCCN1)c1ccc(cc1)-c1ccc(cc1)C(=O)Nc1cccc(c1)C1=NCCN1
Target:
Antibacterial

References

1. Zhu W, et al. Antibacterial drug leads: DNA and enzyme multitargeting. J Med Chem. 2015 Feb 12;58(3):1215-27. 2. Liu YL, et al. Farnesyl diphosphate synthase inhibitors with unique ligand-binding geometries. ACS Med Chem Lett. 2015 Jan 29;6(3):349-54.