TargetMol

BPO-27 racemate

Product Code:
 
TAR-T10591
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10591-1mg1mg£125.00
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TAR-T10591-5mg5mg£230.00
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TAR-T10591-1mL1 mL * 10 mM (in DMSO)£254.00
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TAR-T10591-10mg10mg£309.00
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TAR-T10591-25mg25mg£466.00
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TAR-T10591-50mg50mg£647.00
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TAR-T10591-100mg100mg£867.00
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TAR-T10591-200mg200mg£1,139.00
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TAR-T10591-500mg500mg£1,661.00
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This product comes from: United States.
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Further Information

Bioactivity:
Bpo-27 racemate is an effective CFTR inhibitor with IC50 of 8 nM.
CAS:
1314873-02-3
Formula:
C26H18BrN3O6
Molecular Weight:
548.349
Pathway:
Autophagy; Membrane transporter/Ion channel
Purity:
0.98
SMILES:
Cn1c2c3C(Oc4ccc(cc4-n3c(-c3ccccc3)c2c(=O)n(C)c1=O)C(O)=O)c1ccc(Br)o1
Target:
CFTR; Autophagy

References

1. Kim Y, et al. Benzopyrimido-pyrrolo-oxazine-dione (R)-BPO-27 Inhibits CFTR Chloride Channel Gating by Competition with ATP. Mol Pharmacol. 2015 Oct;88(4):689-96. 2. Snyder DS, et al. Absolute Configuration And Biological Properties of Enantiomers of CFTR Inhibitor BPO-27. ACS Med Chem Lett. 2013 May 9;4(5):456-459.