TargetMol

CYP11B2-IN-1

Product Code:
 
TAR-T10922
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10922-1mg1mg£148.00
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TAR-T10922-2mg2mg£176.00
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TAR-T10922-5mg5mg£229.00
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TAR-T10922-1mL1 mL * 10 mM (in DMSO)£252.00
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TAR-T10922-10mg10mg£322.00
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TAR-T10922-25mg25mg£499.00
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Quantity:
TAR-T10922-50mg50mg£687.00
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Quantity:
TAR-T10922-100mg100mg£938.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
CYP11B2-IN-1 is an effective and selective inhibitor of CYP11B2 with IC50s of 2.3 nM and 142 nM for CYP11B2 and CYP11B1.
CAS:
1356479-78-1
Formula:
C18H18FN3O
Molecular Weight:
311.35
Pathway:
Metabolism
Purity:
0.9839
SMILES:
FC1=CC=C2N=C(C=3C=NC=C(C3)C(O)(C)C)N(C2=C1)C4CC4
Target:
P45

References

1. Hoyt SB, et al. Discovery of Benzimidazole CYP11B2 Inhibitors with in Vivo Activity in Rhesus Monkeys.ACS Med Chem Lett. 2015 Apr 7;6(5):573-8.