TargetMol

DHODH-IN-1

Product Code:
 
TAR-T11019
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11019-1mg1mg£227.00
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TAR-T11019-2mg2mg£306.00
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TAR-T11019-5mg5mg£431.00
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TAR-T11019-1mL1 mL * 10 mM (in DMSO)£465.00
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TAR-T11019-10mg10mg£600.00
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TAR-T11019-25mg25mg£863.00
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TAR-T11019-50mg50mg£1,187.00
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TAR-T11019-100mg100mg£1,581.00
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Further Information

Bioactivity:
DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.
CAS:
1800296-63-2
Formula:
C21H20F3N3O2
Molecular Weight:
403.4
Pathway:
Metabolism
Purity:
0.9956
SMILES:
FC1=CC=CC(F)=C1OC=2C(=NN(C3=NC=C(C=C3F)C4CC4)C2C)OC(C)C
Target:
Dehydrogenase

References

1. Lucas-Hourani M, et al.Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH).J Med Chem. 2015 Jul 23;58(14):5579-98.