TargetMol

hDHODH-IN-4

Product Code:
 
TAR-T11028
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11028-1mg1mg£193.00
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TAR-T11028-5mg5mg£332.00
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TAR-T11028-1mL1 mL * 10 mM (in DMSO)£357.00
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TAR-T11028-10mg10mg£502.00
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TAR-T11028-25mg25mg£768.00
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TAR-T11028-50mg50mg£1,026.00
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Quantity:
TAR-T11028-100mg100mg£1,348.00
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Further Information

Bioactivity:
hDHODH-IN-4 is a potent inhibitor of human dihydrogen dehydrogenase (DHODH). For human recombinant DHODH, its pIC50 is 7.8. hDHODH-IN-4 inhibits measles virus replication with a pMIC50 of 8.8.
CAS:
1644156-56-8
Formula:
C21H24N4O2
Molecular Weight:
364.44
Pathway:
Metabolism
Purity:
0.9931
SMILES:
OC(C=1C=CC=CC1)C=2C(=NN(C3=NC=C(C=N3)C4CC4)C2C)OC(C)C
Target:
Dehydrogenase

References

1. Munier-Lehmann H, et al. Original?2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidine?derivatives?as?inhibitors?of?human?dihydroorotate?dehydrogenase?(DHODH). J Med Chem.?2015 Jan 22;58(2):860-77.