TargetMol

E-7386

Product Code:
 
TAR-T11136
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11136-1mg1mg£142.00
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TAR-T11136-5mg5mg£287.00
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TAR-T11136-10mg10mg£399.00
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TAR-T11136-1mL1 mL * 10 mM (in DMSO)£407.00
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TAR-T11136-25mg25mg£618.00
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TAR-T11136-50mg50mg£849.00
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This product comes from: United States.
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Further Information

Bioactivity:
E-7386 is an oral active CBP/ -catenin modulator.
CAS:
1799824-08-0
Formula:
C39H48FN9O4
Molecular Weight:
725.87
Pathway:
Chromatin/Epigenetic
Purity:
0.9978
SMILES:
CCN1CCN(CC1)C1CN(C1)c1cccc(CN2C[C@H]3N([C@@H](Cc4ccc(O)cc4F)C2=O)C(=O)CN(CC=C)N3C(=O)NCc2ccccc2)n1
Target:
Epigenetic Reader Domain

References

1. Yusaku Hori, et al. E7386, an orally active CBP/beta-catenin modulator, induces T cells infiltration into tumor and enhances antitumor activity of anti-PD-1 mAb in Wnt1 tumor syngeneic mice model. Cancer Res 2017;77(13 Suppl):Abstract nr 5172.