TargetMol

FLT3-IN-3

Product Code:
 
TAR-T11298
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
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CodeSizePrice
TAR-T11298-1mg1mg£158.00
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TAR-T11298-5mg5mg£289.00
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TAR-T11298-1mL1 mL * 10 mM (in DMSO)£305.00
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TAR-T11298-10mg10mg£436.00
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TAR-T11298-25mg25mg£675.00
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TAR-T11298-50mg50mg£922.00
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Quantity:
TAR-T11298-100mg100mg£1,219.00
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Quantity:
TAR-T11298-500mg500mg£2,368.00
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This product comes from: United States.
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Further Information

Bioactivity:
FLT3-IN-3 is an effective FLT3 inhibitor, and the IC50s of FLT3 WT and FLT3 D835Y are 13 and 8 nM, respectively.
CAS:
2229050-90-0
Formula:
C27H38N8O
Molecular Weight:
490.656
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.9997
SMILES:
N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(CN3CCOCC3)cc2)c2ncn(C3CCCC3)c2n1
Target:
FLT

References

1. Guck? T, et al. Discovery of N2-(4-Amino-cyclohexyl)-9-cyclopentyl- N6-(4-morpholin-4-ylmethyl-phenyl)- 9H-purine-2,6-diamine as a Potent FLT3 Kinase Inhibitor for Acute Myeloid Leukemia with FLT3 Mutations. J Med Chem. 2018 May 10;61(9):3855-3869.