TargetMol

FR183998 free base

Product Code:
 
TAR-T11319
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11319-1mg1mg£351.00
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Quantity:
TAR-T11319-5mg5mg£625.00
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TAR-T11319-10mg10mg£867.00
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TAR-T11319-25mg25mg£1,251.00
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Quantity:
TAR-T11319-50mg50mg£1,661.00
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Quantity:
TAR-T11319-100mg100mg£2,223.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
FR183998 free base is an inhibitor of Na+/Ca2+ Exchanger.
CAS:
239440-20-1
Formula:
C17H19Cl2N5O2S
Molecular Weight:
428.33
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
CN(C)CCNC(=O)c1cc(cc(c1)-c1cc(Cl)sc1Cl)C(=O)NC(N)=N
Target:
Na+/Ca2+ Exchanger

References

1. Ohara F, et al. Preischemic and postischemic treatment with a new Na+/H+-exchange inhibitor, FR183998, shows cardioprotective effects in rats with cardiac ischemia and reperfusion. J Cardiovasc Pharmacol. 1999 Dec;34(6):848-56. 2. Ishizaki M, et al. Protective effect of FR183998, a Na+/H+ exchanger inhibitor, and its inhibition of iNOS induction in hepatic ischemia-reperfusion injury in rats. Shock. 2008 Sep;30(3):311-7.