TargetMol

GSK-3β inhibitor 2

Product Code:
 
TAR-T11471
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11471-5mg5mg£111.00
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Quantity:
TAR-T11471-10mg10mg£124.00
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TAR-T11471-25mg25mg£156.00
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Quantity:
TAR-T11471-50mg50mg£229.00
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This product comes from: United States.
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Further Information

Bioactivity:
GSK-3β inhibitor 2 is a BBB-crossing and selective inhibitor of GSK-3β (IC50 = 1.1 nM). GSK-3β inhibitor 2 can be used in studies about Alzheimer's disease.
CAS:
1702428-31-6
Formula:
C14H14N4O3S
Molecular Weight:
318.35
Pathway:
Stem Cells; PI3K/Akt/mTOR signaling
Purity:
0.98
SMILES:
COc1nc(sc1C(N)=O)-c1ccnc(NC(=O)C2CC2)c1
Target:
GSK-3

References

1. Sivaprakasam P, et al. Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core. Bioorg Med Chem Lett. 2015 May 1;25(9):1856-63.