TargetMol

GSK840

Product Code:
 
TAR-T11501
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11501-1mg1mg£111.00
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Quantity:
TAR-T11501-5mg5mg£142.00
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TAR-T11501-10mg10mg£172.00
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TAR-T11501-25mg25mg£229.00
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TAR-T11501-50mg50mg£310.00
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Quantity:
TAR-T11501-100mg100mg£428.00
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This product comes from: United States.
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Further Information

Bioactivity:
GSK840 is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the RIP3 kinase domain (IC50: 0.9 nM), and inhibits kinase activity (IC50: 0.3 nM).
CAS:
2361146-30-5
Formula:
C21H23N3O3
Molecular Weight:
365.433
Pathway:
Apoptosis; NF-κb
Purity:
0.98
SMILES:
CNC(=O)c1ccc2n(cnc2c1)-c1ccc(CC(=O)OC(C)(C)C)cc1
Target:
RIP kinase

References

1. Mandal P, et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. Mol Cell. 2014 Nov 20;56(4):481-95.