TargetMol

Gut restricted-7

Product Code:
 
TAR-T11515
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11515-1mg1mg£197.00
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TAR-T11515-5mg5mg£337.00
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TAR-T11515-1mL1 mL * 10 mM (in DMSO)£370.00
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TAR-T11515-10mg10mg£498.00
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TAR-T11515-25mg25mg£764.00
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Quantity:
TAR-T11515-50mg50mg£1,026.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Gut restricted-7 (GR-7) is a covalent and orally active pan-bile salt hydrolase (BSH) inhibitor. It decreases gut bacterial BSHs and decreases deconjugated bile acid levels in the feces of mice.
CAS:
2553218-46-3
Formula:
C25H40FNaO6S
Molecular Weight:
510.63
Pathway:
Membrane transporter/Ion channel
Purity:
0.9927
SMILES:
O=C(CF)CC[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](OS(=O)(O[Na])=O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C
Target:
Potassium Channel

References

1. Adhikari AA, et al. Development of a covalent inhibitor of gut bacterial bile salt hydrolases. Nat Chem Biol. 2020 Mar;16(3):318-326.