TargetMol

H3B-120

Product Code:
 
TAR-T11529
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11529-1mg1mg£163.00
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TAR-T11529-5mg5mg£269.00
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TAR-T11529-1mL1 mL * 10 mM (in DMSO)£289.00
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TAR-T11529-10mg10mg£402.00
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TAR-T11529-25mg25mg£626.00
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TAR-T11529-50mg50mg£862.00
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Quantity:
TAR-T11529-100mg100mg£1,139.00
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This product comes from: United States.
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Further Information

Bioactivity:
H3B-120 is a highly selective, competitive, and allosteric carbamoyl phosphate synthetase 1 (CPS1) inhibitor (IC50: 1.5 μM; Ki: 1.4 μM) with anti-cancer activity.
CAS:
2194903-42-7
Formula:
C19H24N4O2S
Molecular Weight:
372.49
Pathway:
; Membrane transporter/Ion channel
Purity:
0.98
SMILES:
CN(Cc1ccccc1)C(=O)N1CCC(CC1)C(=O)Nc1nc(C)cs1
Target:
Potassium Channel

References

1. Yao S, et al. Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket. Cell Chem Biol. 2020 Mar 19;27(3):259-268.