TargetMol

Impurity B of Calcitriol

Product Code:
 
TAR-T11643
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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TAR-T11643-100mg100mgEnquire
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TAR-T11643-1mg1mg£638.00
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TAR-T11643-5mg5mg£1,839.00
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TAR-T11643-10mg10mg£2,326.00
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Further Information

Bioactivity:
Impurity B of Calcitriol is an impurity of Calcitriol. Calcitriol is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).
CAS:
66791-71-7
Formula:
C27H44O3
Molecular Weight:
416.646
Purity:
0.98
SMILES:
[H][C@@]12CC[C@H]([C@H](C)CCCC(C)(C)O)[C@@]1(C)CCCC2=C/C=C1/C[C@@H](O)C[C@@H](O)C1=C

References

1. Canalejo et al (2000) The in vitro effect of calcitriol on parathyroid cell proliferation and apoptosis. J.Am.Soc.Nephrol. 11 1865. Beer and Myrthue (2004) 2. Calcitriol in cancer treatment: from the lab to the clinic. Mol.Cancer Ther. 3 373. 3. Krishnan AV, Swami S, Feldman D.Equivalent anticancer activities of dietary vitamin D and calcitriol in an animal model of breast cancer: Importance of mammary CYP27B1 for treatment and prevention.J Steroid Biochem Mol Biol. 2012 Aug 23. 4. Alkharfy KM, Al-Daghri NM, Yakout SM, Ahmed M. Calcitriol Attenuates Weight-Related Systemic Inflammation and Ultrastructural Changes of the Liver in a Rodent Model.Basic Clin Pharmacol Toxicol. 2012 Aug 21.