TargetMol

INH154

Product Code:
 
TAR-T11657
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11657-1mg1mg£136.00
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TAR-T11657-5mg5mg£205.00
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TAR-T11657-1mL1 mL * 10 mM (in DMSO)£226.00
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TAR-T11657-10mg10mg£277.00
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TAR-T11657-25mg25mg£470.00
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TAR-T11657-50mg50mg£651.00
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TAR-T11657-100mg100mg£863.00
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TAR-T11657-500mg500mg£1,661.00
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Further Information

Bioactivity:
INH154 is a potent Nek2 and Hec1 binding (INH) inhibitor with IC50s of 120 nM in MB468 cells and 200 nM in Hela cells for INH.
CAS:
1587705-63-2
Formula:
C22H24N4OS
Molecular Weight:
392.52
Purity:
0.9957
SMILES:
Cc1cc(cc(C)c1-c1csc(NC(=O)c2ccncc2)n1)N1CCCCC1

References

1. Hu CM, et al. Novel small molecules disrupting Hec1/Nek2 interaction ablate tumor progression by triggering Nek2 degradation through a death-trap mechanism. Oncogene. 2015 Mar 5;34(10):1220-30.