TargetMol

JNJ-18038683

Product Code:
 
TAR-T11720
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11720-1mg1mg£97.00
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TAR-T11720-2mg2mg£107.00
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TAR-T11720-5mg5mg£132.00
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TAR-T11720-1mL1 mL * 10 mM (in DMSO)£138.00
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TAR-T11720-10mg10mg£182.00
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TAR-T11720-25mg25mg£303.00
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TAR-T11720-50mg50mg£436.00
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TAR-T11720-100mg100mg£610.00
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Further Information

Bioactivity:
JNJ-18038683 is a 5-Hydroxytryptamine Type 7 (5-HT7) receptor antagonist, with pKis of 8.19, 8.20 for rat and human 5-HT7 in HEK293 cells, respectively.
CAS:
851376-05-1
Formula:
C26H28ClN3O7
Molecular Weight:
529.97
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.9831
SMILES:
OC(=O)CC(O)(CC(O)=O)C(O)=O.Clc1ccc(cc1)-c1nn(Cc2ccccc2)c2CCNCCc12
Target:
5-HT Receptor

References

1. Bonaventure P, et al. Translational evaluation of JNJ-18038683, a 5-hydroxytryptamine type 7 receptor antagonist, on rapid eye movement sleep and in major depressive disorder. J Pharmacol Exp Ther. 2012 Aug;342(2):429-40.