TargetMol

JTV-519 Formate

Product Code:
 
TAR-T11731L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11731L-1mg1mg£227.00
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Quantity:
TAR-T11731L-5mg5mg£422.00
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Quantity:
TAR-T11731L-10mg10mg£597.00
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Quantity:
TAR-T11731L-25mg25mg£1,017.00
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Quantity:
TAR-T11731L-50mg50mg£1,491.00
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Quantity:
TAR-T11731L-100mg100mg£2,201.00
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Quantity:
TAR-T11731L-200mg200mg£3,266.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
JTV-519 Formate is a inhibitor of Ryanodine receptor (RyR).
CAS:
0
Formula:
C26H34N2O4S
Molecular Weight:
470.62
Pathway:
Membrane transporter/Ion channel|Metabolism|Others
Purity:
0.98
SMILES:
O=C(N1CCSC2=CC=C(OC)C=C2C1)CCN3CCC(CC4=CC=CC=C4)CC3.[H]C(O)=O
Target:
Others|Calcium Channel

References

1. Donald J Hunt, et al. K201 (JTV519) suppresses spontaneous Ca2+ release and [3H]ryanodine binding to RyR2 irrespective of FKBP12.6 association. Biochem J. 2007 Jun 15;404(3):431-8. 2. Y-J Chen, et al. Effect of K201, a novel antiarrhythmic drug on calcium handling and arrhythmogenic activity of pulmonary vein cardiomyocytes. Br J Pharmacol. 2008 Mar;153(5):915-25.