TargetMol

K-Ras G12C-IN-4

Product Code:
 
TAR-T11738
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11738-1mg1mg£189.00
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TAR-T11738-2mg2mg£246.00
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TAR-T11738-5mg5mg£369.00
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TAR-T11738-1mL1 mL * 10 mM (in DMSO)£439.00
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TAR-T11738-10mg10mg£517.00
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TAR-T11738-25mg25mg£790.00
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Quantity:
TAR-T11738-50mg50mg£1,050.00
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TAR-T11738-100mg100mg£1,396.00
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Further Information

Bioactivity:
K-Ras G12C-IN-4 is a potent co-valent Inhibitor of KRAS G12C..
CAS:
2376328-55-9
Formula:
C31H33ClN4O4
Molecular Weight:
561.08
Pathway:
MAPK; GPCR/G Protein
Purity:
0.99
SMILES:
COc1cccc2CN(CCc12)C(=O)c1c(C2CC2)n(CC(=O)NC2CN(C2)C(=O)C=C)c2c(C)cc(Cl)cc12
Target:
Ras

References

1. Shin Y, et al. Discovery of N-(1-Acryloylazetidin-3-yl)-2-(1H-indol-1-yl)acetamides as Covalent Inhibitors of KRASG12C. ACS Med Chem Lett. 2019 Aug 20;10(9):1302-1308.