TargetMol

Kira8

Product Code:
 
TAR-T11762L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11762L-1mg1mg£142.00
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TAR-T11762L-5mg5mg£242.00
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TAR-T11762L-1mL1 mL * 10 mM (in DMSO)£298.00
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TAR-T11762L-10mg10mg£329.00
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TAR-T11762L-25mg25mg£550.00
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TAR-T11762L-50mg50mg£755.00
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Quantity:
TAR-T11762L-100mg100mg£1,010.00
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This product comes from: United States.
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Further Information

Bioactivity:
Kira8 is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity (IC50: 5.9 nM).
CAS:
1630086-20-2
Formula:
C31H29ClN6O3S
Molecular Weight:
601.12
Pathway:
Cell Cycle/Checkpoint
Purity:
0.9807
SMILES:
Cc1ccc2c(NS(=O)(=O)c3ccccc3Cl)cccc2c1Oc1ncccc1-c1ccnc(N[C@H]2CCCNC2)n1
Target:
IRE1

References

1. Morita S, et al. Targeting ABL-IRE1? Signaling Spares ER-Stressed Pancreatic ? Cells to Reverse Autoimmune Diabetes. Cell Metab. 2017 Apr 4;25(4):883-897.e8.