TargetMol

LDH-IN-1

Product Code:
 
TAR-T11829
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11829-1mg1mg£242.00
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TAR-T11829-2mg2mg£309.00
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TAR-T11829-5mg5mg£436.00
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TAR-T11829-1mL1 mL * 10 mM (in DMSO)£531.00
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TAR-T11829-10mg10mg£610.00
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TAR-T11829-25mg25mg£922.00
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TAR-T11829-50mg50mg£1,219.00
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TAR-T11829-100mg100mg£1,613.00
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This product comes from: United States.
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Further Information

Bioactivity:
LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).
CAS:
1964515-43-2
Formula:
C30H26N4O4S2
Molecular Weight:
570.68
Pathway:
Metabolism
Purity:
0.9984
SMILES:
NS(=O)(=O)c1ccc(Cc2c(CC3CC3)n(nc2-c2cccc(c2)-c2ccccc2)-c2nc(cs2)C(O)=O)cc1
Target:
Dehydrogenase

References

1. Rai G, et al. Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). J Med Chem. 2017 Nov 22;60(22):9184-9204.