TargetMol

Lefamulin acetate

Product Code:
 
TAR-T11836
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11836-1mg1mg£149.00
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TAR-T11836-5mg5mg£254.00
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TAR-T11836-1mL1 mL * 10 mM (in DMSO)£303.00
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TAR-T11836-10mg10mg£349.00
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TAR-T11836-25mg25mg£526.00
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TAR-T11836-50mg50mg£687.00
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TAR-T11836-100mg100mg£930.00
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Further Information

Bioactivity:
Lefamulin acetate (formally BC-3781 acetate) is a novel pleuromutilin antibiotic and is the first to be used for the systemic treatment of bacterial infections in humans. Lefamulin acetate (BC-3781 acetate) inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, preventing the binding of transfer RNA for peptide transfer.?Lefamulin acetate (BC-3781 acetate) is an orally active antibiotic for community-acquired bacterial pneumonia (CABP) treatment.
CAS:
1350636-82-6
Formula:
C30H49NO7S
Molecular Weight:
567.78
Pathway:
Microbiology/Virology
Purity:
0.9947
SMILES:
CC(O)=O.[H][C@@]12C(=O)CCC11CC[C@@H](C)C2(C)[C@@H](C[C@@](C)(C=C)[C@@H](O)[C@@H]1C)OC(=O)CS[C@@H]1CC[C@@H](N)C[C@H]1O
Target:
ribosome; Antibacterial; Antibiotic

References

1. Veve MP, et al. Lefamulin: Review of a Promising Novel Pleuromutilin Antibiotic. Pharmacotherapy. 2018 Sep;38(9):935-946. doi: 10.1002/phar.2166. Epub 2018 Aug 20.