TargetMol

LMP744 hydrochloride

Product Code:
 
TAR-T11872L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11872L-1mg1mg£168.00
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TAR-T11872L-5mg5mg£262.00
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TAR-T11872L-10mg10mg£369.00
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TAR-T11872L-25mg25mg£571.00
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TAR-T11872L-50mg50mg£784.00
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TAR-T11872L-100mg100mg£1,050.00
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Further Information

Bioactivity:
LMP744 hydrochloride is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity.?
CAS:
308246-57-3
Formula:
C24H25ClN2O7
Molecular Weight:
488.92
Pathway:
DNA Damage/DNA Repair
Purity:
0.9844
SMILES:
Cl.COc1cc2c3C(=O)c4cc5OCOc5cc4-c3n(CCCNCCO)c(=O)c2cc1OC
Target:
Topoisomerase

References

1. Antony S, et al. Cellular topoisomerase I inhibition and antiproliferative activity by MJ-III-65 (NSC 706744), an indenoisoquinoline topoisomerase I poison. Mol Pharmacol. 2005 Feb;67(2):523-30. 2. Antony S, et al. Bisindenoisoquinoline bis-1,3-{( 5,6-dihydro-5,11-diketo-11H-indeno [1,2-c]isoquinoline)-6-propylamino}propane bis(trifluoroacetate) (NSC 727357), a DNA intercalator and topoisomerase inhibitor with antitumor activity. Mol Pharmacol. 2006 Sep;70(3):1109-20.