TargetMol

ML604440

Product Code:
 
TAR-T12079
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12079-1mg1mg£179.00
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Quantity:
TAR-T12079-5mg5mg£302.00
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Quantity:
TAR-T12079-1mL1 mL * 10 mM (in DMSO)£325.00
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TAR-T12079-10mg10mg£436.00
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Quantity:
TAR-T12079-25mg25mg£675.00
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Quantity:
TAR-T12079-50mg50mg£922.00
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Quantity:
TAR-T12079-100mg100mg£1,219.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.
CAS:
1140517-08-3
Formula:
C17H24BF3N2O4
Molecular Weight:
388.19
Pathway:
Ubiquitination; Proteases/Proteasome
Purity:
0.9524
SMILES:
CC(C)C[C@H](NC(=O)C(C)(C)NC(=O)c1ccccc1C(F)(F)F)B(O)O
Target:
Proteasome

References

1. de Bruin G, et al. Structure-based design of ?1i or ?5i specific inhibitors of human immunoproteasomes. J Med Chem. 2014 Jul 24;57(14):6197-209 2. Basler M, et al. Co-inhibition of immunoproteasome subunits LMP2 and LMP7 is required to block autoimmunity. EMBO Rep. 2018 Dec;19(12). pii: e46512.