TargetMol

MM-589 TFA

Product Code:
 
TAR-T12091L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12091L-5mg5mg£1,653.00
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TAR-T12091L-50mg50mg£3,267.00
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Quantity:
TAR-T12091L-100mg100mg£4,488.00
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This product comes from: United States.
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Further Information

Bioactivity:
MM-589 TFA is a potent WD repeat domain 5 (WDR5)inhibitor and mixed lineage leukemia (MLL) protein-protein interaction.
CAS:
2097887-21-1
Formula:
C30H45F3N8O7
Molecular Weight:
686.734
Pathway:
Angiogenesis; JAK/STAT signaling; Chromatin/Epigenetic; Stem Cells
Purity:
0.98
SMILES:
OC(=O)C(F)(F)F.CC[C@@H]1NC(=O)[C@H](CCCNC(=N)NC)NC(=O)[C@@](C)(CCNC(=O)[C@H](NC1=O)c1ccccc1)NC(=O)C(C)C
Target:
JAK

References

1. Karatas H, et al. Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)-Mixed Lineage Leukemia (MLL) Protein-Protein Interaction. J Med Chem. 2017 Jun 22;60(12):4818-4839.