TargetMol

Nacubactam

Product Code:
 
TAR-T12166
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12166-1mg1mg£114.00
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TAR-T12166-5mg5mg£173.00
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TAR-T12166-1mL1 mL * 10 mM (in DMSO)£185.00
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TAR-T12166-10mg10mg£245.00
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TAR-T12166-25mg25mg£420.00
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TAR-T12166-50mg50mg£597.00
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Quantity:
TAR-T12166-100mg100mg£819.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Nacubactam is a potent inhibitor of non-β-lactam-β-lactamase with activity against class A and class C β-lactamases.
CAS:
1452458-86-4
Formula:
C9H16N4O7S
Molecular Weight:
324.31
Pathway:
Microbiology/Virology
Purity:
0.993
SMILES:
NCCONC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OS(O)(=O)=O
Target:
Antibacterial

References

1. Monogue ML, et al. In Vivo Efficacy of Meropenem with a Novel Non-?-Lactam-?-Lactamase Inhibitor, Nacubactam, against Gram-Negative Organisms Exhibiting Various Resistance Mechanisms in a Murine Complicated Urinary Tract Infection Model. Antimicrob Agents Chemother. 2018 Aug 27;62(9). 2. Livermore DM, et al. Activity of OP0595/?-lactam combinations against Gram-negative bacteria with extended-spectrum, AmpC and carbapenem-hydrolysing ?-lactamases. J Antimicrob Chemother. 2015 Nov;70(11):3032-41.