TargetMol

Nevanimibe hydrochloride

Product Code:
 
TAR-T12225L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T12225L-1mg1mg£140.00
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TAR-T12225L-5mg5mg£242.00
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TAR-T12225L-1mL1 mL * 10 mM (in DMSO)£259.00
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TAR-T12225L-10mg10mg£309.00
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TAR-T12225L-25mg25mg£442.00
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TAR-T12225L-50mg50mg£546.00
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TAR-T12225L-100mg100mg£703.00
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This product comes from: United States.
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Further Information

Bioactivity:
Nevanimibe hydrochloride is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).
CAS:
133825-81-7
Formula:
C27H40ClN3O
Molecular Weight:
458.09
Pathway:
Metabolism; Apoptosis
Purity:
0.9925
SMILES:
Cl.CC(C)c1cccc(C(C)C)c1NC(=O)NCC1(CCCC1)c1ccc(cc1)N(C)C
Target:
Apoptosis; Acyltransferase

References

1. LaPensee CR, et al. ATR-101, a Selective and Potent Inhibitor of Acyl-CoA Acyltransferase 1, Induces Apoptosis in H295R Adrenocortical Cells and in the Adrenal Cortex of Dogs. Endocrinology. 2016 May;157(5):1775-88.